BioLines

Where Nature and Science Meet

 

Volume 8.                                  February 2001

 

 

Biotechnology Association for Food, Feed and Fibre

 

 

BioLines is AfricaBio’s ‘Biotechnology Headlines’ – a quick guide to what is topical. By design, the articles

 are not exhaustive, but references are given to follow up points of interest. Let us know what you like and dislike

 about BioLines and what you want to see as part of this service:  biolines1@mweb.co.za

Tel: 012 667 2689  Fax: 012 667 1920  www.africabio.com       Articles are edited to meet space requirements.

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Contents

 

·         EU adopts new GMO directive

·         GM animal feed: Replacing myth with fact.

·         No Increase in Pest Resistance to GM Cotton

·         Resistance management for Bt crops in developing countries

·         GM Foods Are Safe, Says South African Professor

·         ICAC urges GM cotton field trials in Zimbabwe

·         Bad pesticides threaten health in poor nations

 

 

 

·         Golden Rice - at what cost?

·         Kenyan President Speaks on Agricultural Production

·         Starlink Event Results in Little Consumer Action

·         America's Supermarket Guru – on labelling

·         Post-doctoral fellowships at Harvard

·         Meetings and Courses

·         We’re all transgenic!


EU adopts new GMO directive. Brussels, 15 Feb 2001. Deliberate release of genetically modified organisms (GMOs): The Council formally adopted today, with the French and the Italian delegations abstaining, the Directive repealing Directive 90/220/EEC on the deliberate release into the environment of GMOs. With the European Parlia-ment voting in favour of the joint text on 14 February 2001, the Directive is now definitively adopted. The provisions of the Directive will have to be imple-mented by Member States 18 months after its publication in the Official Journal. The Directive deals with experimental releases of GMOs (for research and development purposes) as well as with the placing on the market of GMOs.

In accordance with the precautionary principle, the new Directive requires an environmental risk assessment to be carried out before the authorisation procedure is initiated. It also provides for the phasing out of GMOs containing genes expressing resistance to antibiotics used for medical or veterinary treat-ment. Phasing out shall take place by the end of 2004 in the case of GMOs placed on the market and by the end of 2008 in the case of GMOs released for experi-mental purposes.
GMOs may only be deliberately released or placed on the market in conformity with the procedures laid out in Part B of the Directive (release for purposes other than for placing on the market) or Part C (placing on the market). Each Part comprises a standard procedure at the end of which the lead competent authority (i.e. the Member State having received the notification) gives its consent for the deliberate release or the placing on the market. Whilst only one national competent authority is responsible for granting a consent for the standard procedure under Part B, all the competent authorities are involved for the differentiated (simplified) procedure under Part B and the standard procedure under Part C. Placing on the market involves all the Member States. Consent is given only where possible objections have been answered, or a decision has been taken by committee procedure and the lead competent authority is not opposed to the proposal. Consent is given following extensive consultation (public, scientific committees) and for a maximum period of 10 years for the initial consent. After 10 years a renewed application has to be submitted, which, is subject to the same time-limitation, i.e. 10 years. The consent specifies mandatory monitoring and labelling requirements.
Labelling, at all stages of the placing on the market, is mandatory and it must be stated clearly that "this product contains genetically modified organisms". Thresholds may be established for each product below which adventitious or technically unavoidable traces of GMOs are not to be labelled. Labelling requirements are complemented by provisions on the traceability of GMOs, whereby competent authorities are to keep track of GMOs through the various stages of their market life.

The Directive provides for a mandatory consultation of the public under Part B and Part C both for standard and differentiated procedures. Information on all Part B releases, including their location, shall be made available to the public through public registers. Registers shall also be established to record the location of GMOs grown following Part C authorisation.

Under Part B, the standard procedure is comp-lemented by a differentiated one in terms of the information  requirements or time-periods whereby a committee defines differentiated procedures which could subsequently apply to releases meeting certain safety criteria where sufficient experience exists.
Additional procedures are foreseen for the renewal of consents, for the handling of consents given under the old Directive, and for monitoring and handling of new information and objections to GMOs which have already received consents.
Part C requirements do not apply to products authorised by other Community legislation which is "equivalent" to this Directive as regards risk assessment, risk management, monitoring as appropriate, labelling, information to the public and safeguard clause. A similar derogation from Part B requirements is applicable to medicinal substances.
 

Genetically modified animal feed: Replacing myth with fact. Siglinde Fischer (BioLinX). Feb 8, 2001
Some 200 participants attended the conference on "Genetically Modified Animal Feed: Replacing Myth with Fact" at the Institute for Animal Nutrition of the ETH Zürich on 8 Feb. 2001. The conference was organised by the Institute in collaboration with Internutrition, the Swiss Task Force on Research and Nutrition. Nine experts gave presentations on different facets of the theme. The specific topics were:

·         public opinion regarding genetic engineering in Switzerland,

·         the current situation in the Swiss feed industry, methods of detecting the new genes,

·         the current state of genetic technology relating to crop plants,

·         ideas on the ecology of transgenic plants,

·         what happens to DNA in the intestinal tract,

·         the recurring issue of "food allergies" and

·         the legal and political situation in Switzerland.

Listeners learned that the Swiss population can be divided into "pessimists, pragmatists and optimists" and that these three groups form their opinions on genetic engineering in very different ways. A multi-year study covering the period 1996 - 1999 showed that the % of those who neither accept genetic engineering wholeheartedly nor reject it categorically has risen from 13% to 25%. During the same period, the proportion of those surveyed who generally accept genetic engineering increased slightly from 25% to 29%, while the % of people who expressed disapproval diminished over the three-year period from 62% to 46%.

Speaker Claude Longchamp, GfS Research Institute Bern, sees a potential future for GM goods in a niche market for specialised products. Peter Tesdorpf, President of the Association of Swiss Grain Importers, estimates that Switzerland will continue to procure most of its vegetable protein feed (about 90%) on the world market, noting, for example, that 43% of the soybean products available on that market this year are transgenic. In addition, feeds comprising transgenic varieties of corn and rapeseed are also to be found in European feed troughs. Presently, the only source of gene-tech-free soy seems to be Brazil. However, it is possible to trace the origins of such goods in Switzerland, since samples are taken at a number of different points in the distribution chain, e.g. at ports of entry. It remains to be seen whether this will actually guarantee gene-tech-free protein feed.
Ulrich Hübscher, Director, Inst. for Veterinary Biochemistry, Univ. of Zurich, presented the DNA-based PCR method for detecting the presence of genetically altered organisms. Beat Keller, Director, Inst. for Plant Biology, Univ. of Zurich, provided an overview of the current state and the future of genetic engineering in the field of plant breeding. The primary focus in the commercial sector today is on the enhancement of quality in crop plants: more aromatic and less perishable fruits are currently under development, as are plants potentially capable of supplying basic substances for a variety of industries.
Klaus Ammann, Director, Botanical Garden, Univ. of Berne, emphasised that the question of ecology must not only be addressed for transgenic plants but for every other species and variety of crops as well. All of our crop plants are products of breeding and thus genetically modified; many of them are not native to our region, and many are grown in eco-logically dubious monocultures. Ammann appealed directly to advocates and opponents of transgenic crop plants to work together in developing sustainable and ecologically sounder agricultural production methods.
The question of what happens to DNA in animals' bodies was the focus of the presentation by Caspar Wenk, Director, Inst. for Farm Animal Research, ETH Zürich. Scientists now know that genetic material is digested almost entirely in the stomach and the small intestine. It is possible, however, that fragments of DNA comprising tens to hundreds of genes are absorbed at least temporarily by cells (primarily immune cells), where they are broken down in a prolonged process. As this is a completely natural process, which applies to all DNA ingested with food, there is no extraordinary risk associated with the digestion of transgenic crop plants. In addition to the roughly 5 to 10 g of DNA consumed by a dairy cow in the course of one day, the animal also digests as much as 200 g of bacterial DNA from the rumen and intestines along with several grams of its own DNA contained in abraded cells.
Karen Aulrich, Inst. for Animal Nutrition, Federal Inst. for Agricultural Research, Braunschweig presented numerous feeding studies involving cattle, hogs and poultry. According to the findings of this research, transgenic crop plant varieties and their conventional parent varieties show fully comparable nutritional-physiological properties - a clear indic-ation that the introduction of new genes has produced no undesirable changes in the metabolism of these transgenic varieties. Transgenic varieties of corn earned significantly higher marks with respect to contamination with mycotoxins, with levels as much as 90% lower than those of non-transgenic varieties. Absence of tunnels bored by feeding caterpillars left little opportunity for fungal growth.
The issue of food allergies was addressed by Beda Stadler, Inst. for Immunology and Allerology, Inselspital, Bern. He showed that food allergies are actually quite rare, and that the plant proteins which trigger them, are comprised within a small group of thoroughly researched proteins. In his opinion, the GM foods currently available on the market do not cause new allergic responses, as humans have been in contact with all of the proteins introduced to these plants for a long time. The proteins come from bacteria we routinely consume every time we eat lettuce or radishes. None of these proteins exhibits such typical allergenic features as high concentration in raw matter (e.g. Milk, eggs, soy beans) and strong resistance to digestive action in the intestinal tract.
Jacques Morel, Vice-Director, Federal Agency for Agriculture, reported on the current legal and political situation with regard to "GM feeds" in Switzerland. The law requires that raw materials and single-component feeds containing more than 3% of transgenic material and mixed feeds containing more than 2% of such material must be labelled accord-ingly. Seed produced abroad, e.g. for corn and soy-beans, may contain no more than 0.5% of transgenic material. Negotiations on ways to close the remain-ing regulatory gaps are to begin shortly. The concluding panel discussion was devoted to a several remaining unresolved questions, such as why a Swiss farmer should plant transgenic varieties. It became clear that only a few aspects of currently available varieties are of interest under the conditions pre-vailing in Switzerland, one of these being reduced mycotoxin contamination. Participants generally agreed that future varieties, including plants capable of producing precursors for the pharmaceutical, cosmetics and paint industries, could be of interest. Klaus Amman repeated his warning against the "continued ideological trench warfare" between the advocates and opponents of genetic engineering.
At the end of this well-organised conference, participants were give an opportunity to sample genetic variety in the form of colourful corn cobs and to pursue further discussion during an evening snack.

 

Study Shows No Increase in Pest Resistance to GM Cotton Nov 20, 2000 Susan McGinley,  mcginley@ag.arizona.edu
Results of a new study published in the Nov. 21 issue of the Proceedings of the National Academy of Sci-ences may diminish fears about one of the potential pitfalls of GM crops. Bt cotton has a gene transferred from the bacterium Bt (Bacillus thuringiensis) that lets plants produce a natural insecticide, thus reduc-ing reliance on sprays of chemical insecticides. A major concern is that pests could quickly evolve resistance to the Bt toxin in GM cotton. This has not happened yet, according to the new study.
Bt cotton was first grown commercially in the US in 1996 and has accounted for more than half of the cotton acreage in Arizona since 1997. For several years, a team of scientists in Arizona has tracked resistance to Bt cotton in pink bollworm caterpillars, which attack bolls of cotton in the southwestern U. S. The estimated frequency of a gene conferring resistance to the toxin in Bt cotton was about 1 in 10 for pink bollworm caterpillars from 10 Arizona cotton fields in 1997, which was was higher than expected. This is roughly 100 times higher than estimates for other pests of Bt crops. Based on this relatively high estimate and projections from com-puter models, rapid increases in resistance were expected in subsequent years. Surprisingly, the estimated frequency of resistance did not increase from 1997 to 1999 and Bt cotton remained effective against pink bollworm.
"Bt cotton is working extremely well in Arizona," said Bruce Tabashnik, UA entomology professor and lead author of the study. "Resistance has not evolved as quickly as expected," said Tabashnik. To help delay resistance, the EPA requires that farmers who grow Bt cotton must also plant refuges of cotton without Bt toxin to allow survival of pests that are not resistant.
To understand why resistance has not evolved as predicted, the scientists are developing new models that incorporate the latest data and are expanding field monitoring and research on resistance genetics and ecology. Recent results suggest that on ordinary cotton resistant pests suffer a competitive disadvant-age relative to non-resistant pests. Nonetheless, the scientists continue to prepare for resistance problems in the future. "Bt cotton has helped to reduce insect-icide use in Arizona cotton to the lowest levels in the past 20 years," said coauthor Larry Antilla of the grower-supported Arizona Cotton Research and Protection Council. "This benefits the public, farm workers, and the environment." (Tabashnik et al. Agricultural Sciences. Frequency of resistance to Bacillus thuringiensis in field populations of pink bollworm. Proc. Natl. Acad. Sci. USA, Vol. 97, Issue 24, 12980-12984, Nov 21, 2000)

 

Resistance management for Bt crops in developing countries. Mike Cohen m.cohen@cgiar.org
Transgenic crop varieties with toxin genes from Bacillus thuringiensis (Bt) can be a valuable com-ponent of integrated pest management, but these varieties must be carefully designed and deployed so as to delay the increase of toxin resistance in pest populations. The "high dose/refuge" resistant management strategy for Bt crops is being enforced in the USA, Canada, and Australia (Ed: and South Africa). Under this strategy, farmers who grow a Bt crop must also maintain a refuge consisting of non-Bt varieties of the same crop. The question is often raised as to how to implement the high dose/refuge strategy in developing countries, where there are many millions of small farmers and where govern-ments have a limited capacity to influence farmer
practices. In a new review, "Bt rice: practical steps to sustainable use", Fred Gould, J.S. Bentur and I make four recommendations about the design and deploy-ment of Bt rice varieties in developing countries. The review, published in International Rice Research Notes, is available online at http://www.cgiar.org /irri/irrn25-2.htm. We recommend four actions that seed suppliers and governments can take to imple-ment a functional high dose/refuge strategy in developing countries. The recommended actions do not require the active cooperation of farmers.  We hope that our review will stimulate discussion on the problem of implementing resistance management for Bt crops in developing countries, and that this dis-cussion will lead to a widely accepted set of recommendations for seed suppliers and gov-ernments. 
Four practical recommendations for promoting the sustainable use of Bt rice can be made, on the basis of our specific knowledge of the biology of rice stem borers and the principles of resistance management:
1. Do not release Bt varieties that do not have a high dose of toxin. Toxin titres of 2 ug/g of leaf fresh weight or 0.2% of soluble leaf protein are attainable in rice, and have been shown to act as high doses against most pests in other crops.
2. Release only Bt cultivars that have two Bt toxin genes. The genes should not be closely related to each other, and both should be expressed at a high dose. Two-toxin cultivars require smaller refuges to achieve successful resistance management.
3. Do not release Bt-transformed versions of all popular rice varieties. Some popular non-Bt varieties should remain available, to improve the chances that some non-Bt rice fields (refuges) will exist in all villages. Sufficient seed supplies of the non-Bt varieties should be maintained.
4. Implement a resistance monitoring program. Several methodologies can be used to monitor pest populations for the evolution of resistance to Bt cultivars. The use of "sentinel plots," in which insect damage is monitored in unsprayed fields of Bt cultivars, is perhaps the most practical for rice-growing areas. Resistance monitoring programs can serve as an early warning system for governments and farmers, and provide valuable information for improved deployment of future pest-resistant cultivars.

Genetically Modified Foods Are Safe, Says South African Professor Prof Jennifer Thomson, Univ of Cape Town, Feb. 2001. http://www.science inafrica.co.za
Humans have been meddling with nature since time immemorial. A chihuahua would hardly compete with the wolves from which dogs were bred. Maize would not be recognised by the ancient middle Americans who began breeding from its progenitor, teosinte, some 7 500 years ago. And wheat would probably not be passed by food regulatory authorities if it were introduced today because of the numbers of people who are allergic to it. Breeding programmes that have given us nearly all the food we eat today are inherently hit or miss affairs.

It takes two different varieties of a plant to breed. One might have a high yield and the other might be resistant to an insect pest. Breeders cross-pollinate these two varieties, obtain seeds and plant them.  The plants that grow will be a random mix of the genes from the parent plants. The breeders will select those plants that have high yields and insect resistance – the desired characteristics.
Unfortunately, due to the randomness of the process, those plants might be sensitive to a virus that was not a problem in either parental strain but, when their genes were mixed, it became a problem. Therefore some selected plants will have to be discarded and others selected. This is an extremely inexact process and very time consuming. However, it works. Genetic engineering can be used to speed up this process. It will never displace breeding - indeed genetic engineers are heavily dependent on plant breeders to ensure any introduced gene exists and operates in concert with the other genes of the plant.
Genetic engineering of plants enables scientists to take any gene from any living being and introduce it into a plant. The resulting transformed, or transgenic, plant is referred to as a genetically modified (GM) plant.
The genes that are introduced are very carefully studied – their entire DNA sequence is determined. Therefore this part of the process, unlike breeding, is extremely precise.  What is not precise is where the gene is introduced into the plant. Although scientists are working on improving this aspect, at present genes are largely inserted into plant DNA in a random fashion. Therefore, once the genes have been introduced, a great deal of work is required to ensure that the inserted genes and the plant's own genes work harmoniously together.
Critics of GM plants often cite this randomness of insertion as being totally unacceptable. However, they omit to add that in nature genes jump all over the place within living organisms. Indeed some of the plants in your garden, especially those with varie-gated leaves, may well be the result of jumping genes.
Most traits introduced into plants to date involve herbicide tolerance and resistance to insects. These are called "input traits". They are traits that improve the productivity of a crop and decrease dependency on chemical pesticides and herbicides. They mainly benefit seed companies and farmers, and this has led to much of the antagonism against GM crops - people see the big corporations making fat profits and they see no gain for themselves, the consumers.
However, let us not lose sight of the fact that in Africa farmers are often also the consumers. A 2nd generation of GM crops are in the pipeline. These contain the so-called "ouput traits" which will have more obvious advantages to consumers. These include "golden rice" which will increase vitamin A  availability and help prevent millions of Asian child-ren from going blind.  They include potatoes with a higher starch content that absorb less oil during the frying process; tomatoes that taste better and rot less, and oils with more healthy unsaturated fats. 

So why do newspaper headlines scream "Are you eating Frankenstein foods?', "Beware of genetic pollution!" and "Genetically modified foods reap a harvest of fears".  Why don't we read headlines such as "Genetically modified rice saves millions of Asian children from blindness?' or "Genetically modified sweet potatoes save East African crops from virus plague"?  Certainly bad news sells better than good news.

Let us look at safety of foods derived from GM crops for human and animal consumption. First of all it is important to realize that there is no such thing as safe food - there is only the safe use of food. You or I could probably die, or at least become very ill, if we ate nothing but eggs.  However, GM plants are treated as if they were toxins - the only plants (or foods derived from them) to be treated in this way. They are subjected to a battery of toxicological tests, including ones that can detect potential long-term effects on humans or animals. Only then are they declared safe.  By comparison, when a new food is introduced into the market, not derived by genetic modification, no such tests are required. Take for example one of my very favourite foods, the peppadew. How long has that been on the market and who has checked that it might not have any long-term adverse effects on humans? Please don't misunderstand me - I am quite sure peppadews are perfectly safe for human consumption - but the fact is they haven't been tested in the way GM plants are.
Let us now look at how safe GM crops are for the environment. As most GM crops are either resistant or tolerant to insects and herbicides, I will concentrate on these. Can animals die from eating an insect resistant plant? No, the toxic protein produced by the plant is specific to certain groups of insects and not to animals.  Can non-targeted insects be killed by insect resistant crops? Insect resistant crops produce one extra protein that causes the death of insects that feed on that plant. However, insects that eat the pollen produced by the insect resistant crops could be killed. There was an outcry in the media when a study showed that pollen from insect resistant maize could kill Monarch butterfly larvae.  "GM pollen that can mean a cloud of death for butterflies" was one such headline. What wasn't disclosed was that this was a laboratory study in which Monarch butterfly larvae were force-fed leaves covered with the pollen. The press omitted to comment on the fact that subsequently 20 or so field trials had shown that not only was there no effect on Monarch butterfly larvae but that the larvae preferentially choose not to eat leaves that contain pollen - whether genetically modified or not.  In fact, since the widespread acceptance of insect resistant crops in the USA, populations of Monarch butterflies have increased, possibly due to the decrease in the use of insecticides.
What about herbicide resistance? Cynics say that this is a ploy by chemical companies to force farmers to buy their herbicide. Certainly chemical companies wish to make profits - that's what their shareholders require - but in the case of the herbicide Roundup it is less harmful than many other weed killers as it is readily biodegradable. The introduction of herbicide resistant crops has caused a decrease in the number of times crops are sprayed, and as many sprayings are from airplanes which spread the chemicals far and wide, that is clearly beneficial to the environ-ment, and to the health of people on neighbouring lands.
However, I am not saying that all GM crops are safe in all environments. Each must be looked at carefully on a case by case basis. For instance, it would be foolhardy to allow the release of a herbicide resistant plant if it could cross-pollinate a potential weed.   Although such herbicide resistant weeds could potentially be eliminated by other weed killers, it is still not a good idea.  In South Africa we have a Genetically Modified Organisms Act which is administered by the Department of Agriculture. They have the responsibility of considering each applic-ation for a field trial or commercial release on a case-by-case basis.  
I am also not saying that the GM crops are the only answer to food shortages in. It has been calculated that if we continue with current agricultural practices Africa south of the Sahara will have a grain shortage of 88.7 million tons by the year 2025. Clearly some-thing has to be done. Certainly there is enough food produced in the world to feed everyone - but the problem is how to get it to the people in need? Certainly we should stop wars, eliminate corruption so that food gets to the right people, build roads and rails to transport the food, but how long will that take?  In the meantime, GM crops, that increase yields, are just one of the ways in which we can tackle the problem. Just because Europe has enough food and doesn’t want GM foods, should we allow them to dictate to us as to what is best for Africa?

 

ICAC urges GM cotton field trials in Zimbabwe. 13 FEB 2001 © 2001 PJB Publications
The International Cotton Advisory Committee (ICAC) believes that field trials of genetically modified (GM) cotton should be carried out in Zim-babwe in order to ascertain their suitability to the region. The ICAC also suggests the country's govern-ment should undertake a review of the current bio-technology regulations.  It should be established whether bollworms and related insects are damaging enough to warrant the introduction of GM cotton in Zimbabwe and eastern Africa, says ICAC executive director Terry Townsend. The ICAC estimates that around 12% of the global cotton area in 2000 was devoted to GM varieties and that in five years, GM cotton will account for half of the world's production. The ICAC supports the use of GM cotton, highlight-ing the "extraordinary benefits in terms of reduced pesticide applications and improved quality".

 

Bad pesticides threaten health in poor nations-FAO. Checkbiotek.org 02 Feb 2001, News Release Reuters - Around 30 % of pesticides marketed in developing countries, with an estimated market value of $900 million annually, do not meet inter-nationally accepted quality standards, the UN’s FAO said on Thursday. "They are posing a serious threat to human health and the environment. These poor-quality pesticides frequently contain hazardous sub-stances and impurities that have already been banned or severely restricted elsewhere,'' said Gero Vaagt of Rome-based FAO's pesticide management group. Such pesticides often contribute to the accumulation of obsolete pesticide stocks in developing countries, he added.  The global market value for pesticides is estimated at $32 billion in 2000, with the share of developing countries around $3 billion. In develop-ing countries, pesticides are mainly used for agri-culture, but also for public health, such as insect-icides for controlling insect spread of malaria. Possible causes of low quality of pesticides can include poor production and formulation and the inadequate selection of chemicals. 
"In many pesticide products, the active ingredient concentrations are outside internationally accepted tolerance limits,'' said David Heymann, executive director of WHO's communicable disease activities. "In addition, poor quality pesticides may be contam-inated with toxic substances or impurities,'' he added. When the quality of labelling and packaging is also taken into account, the proportion of poor-quality pesticide products in developing countries is even higher. "The labelling, often written in improper language, fails to provide data on the active ingred-ient, application, date of manufacture and safe hand-ling of the chemical,'' the UN agencies said. For the consumer, the label is often the only source of pro-duct information that can guarantee safe and effect-ive use of the chemical. Falsely declared products continue to find their way to markets for years without quality control. FAO and WHO said that the problem of poor-quality pesticides was particularly widespread in sub-Saharan Africa, where quality control was generally weak.

 
Golden Rice - at what cost?
Hans R. Herren, International Centre of Insect Physiology and Ecology, Kenya. From Klaus Amman, Feb 2001
The question here is: at what/whose cost will the Golden Rice (and for that matter any biotech product /solution) be further developed? Given the shortage of funding for research, capacity building and development (implementation), I would like to suggest that should any further development in the biotech (read GE for Golden rice, Bt maize, cotton etc.) continue, it must be from private sector funds only. It must be additional to presently available funding for development issues, and the private sector must match dollar for dollar costs for in-dependent evaluation of new technologies/products and for all environmental and health impact studies. None of this necessary research should be funded from public funds, as at the end of the day it is the private sector who will benefit from selling the technology, should it prove to be of social, econo-mical and environmental value to humanity. We already know today that most of the problems that are to be addressed via Golden Rice and other GMOs can be resolved in matter of days, with the right political will. The problem is not scientific, it is social and economic. It is of a nature that requires a bit of courage from the political establishment, which unfortunately is totally lacking. The public at large in the industrialized countries is also to blame: to prefer short-term tax breaks and extra luxuries to few sacrifices for an assurance of a sound world for all of its children. If our fathers had had as little foresight as our own generation of (so called) leaders today, most of us would not even be here today to lament over this state of affairs. The greed that has brought us the pesticides that were marketed without proper testing, BSE and now the new miracle crops, will bring more of the same disasters under different incarnation. A good example for misguided invest-ment is in vaccine research, malaria and others: millions die every year, with no hope for any improvement, because the simple activity of reducing the source of the infection, i.e., the mosquito, has been forgotten. The development of an effective vaccine, just as the development of new miracle crop varieties, does not automatically solve the problem, the social and economical constraints are often far more difficult to overcome, and so need to be given far more attention. No one seems to be learning from the past experiences, be it the green revolution or the yellow fever vaccine, or untold others, all great achievements at first glance, but with meager results, once all has been considered. Sad indeed, and what have we learned? hherren@icipe.org (Ed: Can anyone clarify the failure of the yellow fever vaccine?)

 

Kenyan President Speaks on Agricultural Production. FSN Newswire. January 02, 2001

Nairobi – On Sunday, Kenyan President Daniel arap Moi pleaded with local government officials to help assist farmers in the country to boost current food expectations. Currently, food crop production is on the decline in Nairobi.  Moi’s remarks came at the State House in Nakuru in central Kenya. He stated that Kenya was not an industrialized country and that they must rely heavily on their agricultural production for subsistence, and as the country’s economic support. Moi also advised that more attention be placed on cotton cultivation, to further improve the local textile industries. He added that the country's livestock production was required to be further improved to get extra foreign exchange and pledged the government's commitment to reviving the Kenyan Meat Commission. Moi gave Botswana as an example which slaughters 8,500 cattle per day for export in the European markets. At the same time, the president also called for the conservation of forests, particularly in water basin areas.

 

Starlink Event Results in Little Consumer Action Copyright © 2001 CountryRoads Network, AgJournal, Feb 10, 2001
Despite the media blitz on StarLink corn, most U.S. consumers have not altered their food-buying behavior at all, continuing to place top priority on taste, value, nutrition and convenience. That was the conclusion of a survey of a representative sample of U.S. adults conducted days after the news broke of Starlink corn, approved for animal feed but not human use, in taco shells, said Dr. Thomas Hoban, the North Carolina State University sociologist who conducted the survey on behalf of the Grocery Manufacturers Association.
Sixty-seven % of consumers answering the survey said they would continue to consume biotech products that had been engineered to resist insects, and only 3 % said biotechnology was their most serious concern about food safety. "StarLink did not change U.S. consumer attitudes toward genetically modified  (GM) corn," Hoban told a February 1, 2001, conference on genetically modified organisms at the Univ. of Minnesota. "Although 53 % had heard about it [the StarLink incident], 95 % took no action." Of the 5 % who did, in most cases the action was seeking more information about GM food.
Survey interviewers were trained to try and draw out comments about biotechnology without influencing the answers. Even so, the issue was seldom mentioned, Hoban said. Interviewers were even instructed to treat any reference to avoiding tacos or taco shells as evidence of the controversy's impact without much measurable result.
"In response to the query, 'Biotechnology will benefit people like me within the next five years,' the nations with the highest numbers of positive responses were China, Thailand and the Philippines," Dr. Hoban said. He compared the controversy over GM crops to similar controversies that greeted other technological innovations. "When microwave ovens were first introduced, some people wouldn't use them because they were afraid of radiation," he said. "And there were all these signs warning people with pacemakers of the presence of a microwave oven." At one time, Dr. Hoban added, Massachussetts banned pasteuriz-ation of milk because pasteurization was supposed to destroy important nutrients in the milk.

Meanwhile, a report from 13 of the nation's leading agricultural and commodity organizations and the Council for Biotechnology Information  (CBI) indicates the recent controversy that has swirled around StarLink corn has done little to dampen farmers' enthusiasm for biotechnology. In an on-line survey by AgWeb.com, conducted the week of November 17, 2000, farmers were asked how the recent controversy surrounding biotechnology would affect their seed corn selections for 2001. Results showed that 45 % would plant either the same or a greater percentage of biotech corn for the coming year. In comparison, 29 % said they would plant a reduced percentage or no biotech corn in 2001. "The publicity surrounding StarLink hasn't shaken our confidence in thevalue of biotechnology one bit," says Ron Heck, who grows corn and soybeans near Perry, IA. "Our farm is located very close to the western Corn Belt, where corn borers can be a real problem. Bt corn provides a safe, economical and environmentally friendly option for controlling these pests." Seed company sales figures confirm this trend.
"Our biotech products are an important part of  our business," says David Thompson, director of marketing communications with Stine Seed in Adel,  IA. "Our sales grew last year and we're anticipating they'll grow again this year. Farmers have been very pleased with products of biotechnology and that certainly has been reflected in our sales figures." Scott Beck, vice president of Beck's Hybrids in Atlanta, IN, says sales of Roundup Ready soybean seed are up 8 % over last year. Roundup Ready varieties, he adds, account for 94.5 % of the company's soybean seed sales.
The adoption of biotech products in the cotton industry over the past few years has been rapid and widespread. Annual USDA Cotton Varieties Planted Reports show plantings of biotech varieties have increased from 13 % of total cotton acreage in 1996 to 70 percent in 2000. "Looking ahead to the 2001 growing season, we're again seeing increased  sales of biotech varieties," notes Steve M. Hawkins, president of Delta and Pine Land Company.

America's Supermarket Guru Warns: 'GMO Labeling - the FDA Isn't Listening' 16 Feb 2001. PR Newswire. Leading the fight to convince the FDA that consumers want mandatory labeling of GM foods, Phil Lempert, America's Supermarket Guru is going coast to coast with his message. "There is no question that the American consumer has the right to know if any of the foods we are consuming contain GM ingredients. To insure that our government knows how strongly we feel about mandatory labeling of these foods, we must band together to let the new administration and Secretary of Agriculture, Ann Veneman know how strongly we feel before regulations are finalized on April 3, 2001.”  Through day-to-day contact with consumers Lempert has learned that, in theory, Americans are pro-biotech. They know that in mapping the genome we have the ability and the science to uncover and cure chronic diseases like cancers, heart disease, diabetes and obesity, but they are also demanding full disclosure of these foods, their benefits and any potential downsides.

On January 18, 2001, the FDA published its proposed ruling concerning Bio Engineered Foods. Lempert calls this grace period "a call to action for consumers who want their voices heard." "The American consumer has the right to know if any of the foods we are consuming contain GM ingredients. Over the past decade more consumers than ever have relied on the ingredient panel and nutritional facts labeling to help guide them through the maze of the supermarket. The American Supermarket Industry cannot afford to loose consumer confidence," says Lempert.  He encourages consumers to log on to his SupermarketGuru.com website, and have their opinions count with the FDA. Phil Lempert has been analyzing consumer habits and food industry trends for the last 25 years. He is America's Supermarket Guru: SupermarketGuru.com


Post-doctoral fellowships at Harvard University. Deadline 15 March 2001. The Science Technology and Innovation (STI) Program offers post-doctoral fellowships in Science, Technology and Development under the auspices of the Biotechnology and Globalization project supported by the Rockefeller Foundation. The aim of the project is to provide research-based information to policy-makers and the general public on the role of biotechnology in the global economy with emphasis on its implications for developing countries. Fellow-ships are offered for one year, with an option for renewal. They seek applicants from developing countries in fields related to the application of science and technology to development, with emphasis on biotechnology and globalization. The STI Program offers 10-month stipends of $31,000, for the period of September 2001 through May 2002. Each applicant should submit: 1) a 3 to 5 page research proposal highlighting the relevance of the candidate's research interests to the Biotechnology and Globalization project <http://www.cid.harvard. edu/cidbiotech/index.html>; 2) a Curriculum Vitae; 3) three letters of recommendation submitted directly, by the referees, to the address below; 4) a list of the names of the referees; and 5) a writing sample, preferably an off-print of a published article, or a dissertation chapter. Mailing Address: Program Coordinator, Science, Technology and Innovation Program, Center for International Development at Harvard University, 79 John F. Kennedy Street, Cambridge, MA 02138 USA

 

Meetings and Courses

 

2 - 6 April, Florence, Italy Workshop/Biosafety 2 "Advanced Research in Risk Assessment and Management for the Environmental Release of Genetically Modified Organisms (GMOs): Identification of Main Areas for Future Investigation"  E-mail: courses@icgeb.trieste.it

 

9 - 12 April. Trieste, Italy. Theoretical Course "RNA Structure and Function" Organiser: Glauco Tocchini-Valentini (Institute of Cell Biology/CNR, Italy) E-mail: courses@icgeb.trieste.it

 

23 April - 4 May. Trieste, Italy. The Third Borsellino College on Neurophysics "Evolution of Intelligent Behaviour" E-mail: passarel@ictp.trieste.it

 

29 June - 6 July. Trieste, Italy. Practical Course "Bioinformatics: Computer Methods in Molecular Biology" E-mail: courses@icgeb.trieste.it

 

1 - 7 September, Florianapolis, Brazil. 19th International Papillomavirus Conference E-mail: hpv2001@jz.com.br

 

11-13 September, Trieste, Italy. International Conference on Globalization of Research and Development: Challenges and Opportunities for Developing Countries. http://www.ictp.trieste.it /TWAS/TWAS.html

 

8 - 10 September. Trieste, Italy. Final Meeting of the EULEISH Leishmania major Genome Sequencing Project  E-mail: bruschi@icgeb.trieste.it

 

9 - 15 September. Warsaw, Poland. Second International Conference "Inhibitors of Protein Kinases” (IPK-2001) E-mail: ipk2001@icm.edu.pl

 

17-21 September. Trieste, Italy. Review Lectures and Practical Course "Universal Nucleotide Chips for Comparative Sequencing, SNP Genotyping and Discovering Splice Variants" E-mail: courses@icgeb.trieste.it

 

1 - 12 October. Trieste, Italy. College on Biophysics "From Molecular Genetics to Structural Biology"
 E-mail: de_comelli@ictp.trieste.it

 

15 - 17 October. Trieste, Italy. Workshop "The Biology of the Post-Genomic Era" E-mail: lippolis@icgeb.trieste.it

 

29 October - 9 November. New Delhi, India Practical Course "High Level Expression of Heterologous Proteins in Yeast".  E-mail: chatterj@icgeb.res.in

 

4 - 13 November. Dhaka, Bangladesh. Practical Course "Novel Genetic Markers for Crop Improvement"  E-mail: baptc@bd.drik.net, hadi@bttb.net, botany@du.bangla.net

 

12 - 16 November. Caracas, Venezuela. Workshop/Biosafety 3 "Advanced Issues on Biosafety: Risk Monitoring and Public Perception of Biotechnology" E-mail: efra63@hotmail.com

 

19 November - 2 December. New Delhi, India. Practical Course "Plant Gene Expression" E-mail: chatterj@icgeb.res.in

 

9 - 13 December. New Delhi, India. Symposium "Molecular Medicine" E-mail: chatterj@icgeb.res.in

 

15-17 October. Egypt. Biotechnology and sustainable development: voices of the South and the North. Dr. Ismail Serageldin, Tel.: (+20-2) 572 4358/5725785/5735829 Fax: (+20-2) 572 8099  E-Mail: icarda-cairo@cgiar.org

 

May 31 - June 1, UK. Seeds of Opportunity: the Role of Biotechnology in Agriculture.   The Brunei Gallery, SOAS (central London).  This conference will bring together leading international figures in agricultural biotechnology in order to demystify this technology and to discuss its potential advantages and disadvantages. Two Nobel Laureates will speak at the conference: Norman Borlaug, Nobel Peace Prize Winner and "Father of the Green Revolution" and Professor Sir Harold Kroto, Nobel Prize Winner in Chemistry.  http://www.seedsofopportunity.com/ or email andrew.kendall@kendallspr.co.uk

 


We’re all transgenic! From Tony Jackson 13 Feb 2001, AgBioView

One of the more remarkable findings from the just published human genome sequence is that several hundred human genes were apparently derived from bacteria via horizontal gene transfer. It seems that each of us - yea, even Lord Melchett - is a natural genetically modified organism. (http://www.nature.com/genomics/human/)